Patient: 52 years of age, female, BCVA 0.8 at OD, Light Perception at OS. Ocular Medical History: since 4 weeks proptosis, limited ocular motility, and blurred vision. General Medical History: history of previous breast cancer. Main Complaint: proptosis. Purpose: to present severe proptosis in mamma carcinoma. Methods: Colour Photography Anterior Segment, cranial MRI. Findings: Colour Photography Anterior Segment: massive proptosis, chemosis, corneal ulceration. Cranial MRI: orbital esion of 1.7 x 7.9 x 7.7 mm in left fossa temporalis, infiltration of temporal muscles, and intracranial extension with 3.1 x 3.1 x 5.0 cm. Discussion: Magliozzi et al. (1) reported about patients with orbital metastasis . He showed that the primary tumor site was breast in 39%, kidney in 11%, lung in 9%, and skin in 6%. The most frequent clinical findings were proptosis in 73%, limited ocular motility in 55%, blepharoptosis in 46% and blurred vision in 43%. After the orbital diagnosis 90% of patients died with an overall mean survival time of 13 months. Literature: (1) Magliozzi P, Strianese D, Bonavolontà P, Ferrara M, Ruggiero P, Carandente R, Bonavolontà G, Tranfa F. Orbital metastases in Italy. Int J Ophthalmol. 2015 Oct 18;8(5):1018-23.