Patient: 30 years of age, male, BCVA 1.0 at OD, 0.5 at OS. Ocular Medical History: biopsy and extensive systemic investigation revealed large conjunctival lesion on lower eyelid to be a primary conjunctival epithelial cell carcinoma. General Medical History: empty. Main Complaint: a large conjunctival lesion on lower eyelid of OS. Purpose: to demonstrate a large conjunctival lesion on lower eyelid revealing as epithelial carcinoma of the conjunctiva. Methods: Colour Photography Anterior Segment, Orbital CT Findings: Colour Photography Anterior Segment: vascularized mass in the palpebral conjunctiva. Orbital CT: mass in the lower palpebral conjunctiva penetrating into the orbit (*). Discussion: Conjunctival intraepithelial neoplasia (CIN) is a frequent conjunctival tumor with an incidence of 1 to 2,8 per 100.000 subjects per year. Following excision alone recurrences are frequent. An effective postsurgical recurrence prevention is therefore highly desirable. Cartsburg et al.(1) reported the effectivity of postsurgical chemotherapy of conjunctival squamous cell carcinoma in situ (CIN) with mitomycin C eyedrops. He found, that adjuvant topical mitomycin C appears to be effective in the prevention of recurrences of conjunctival CIN after surgical removal, and that at least 4 cycles of topical MMC are required to prevent local recurrences in the long term. Literature: (1) Cartsburg O, Kersten A, Sundmacher R, Nadjari B, Pomjanski N, Böcking A. Treatment of 9 squamous epithelial carcinoma in situ lesions of the conjunctiva (CIN) with mitomycin C eyedrops in cytological and DNA image cytometric control. Klin Monbl Augenheilkd. 2001 Jun;218(6):429-34.