Atlas of Ophthalmology

Irvine-Gass Syndrome in a vitrectomized patient

Retina -> Enfermedades Maculares Adquiridas
A 71-year-old pseudophakic man underwent successful pars plana vitrectomy and laser photocoagulation of retinal tears followed by 14% C3F8 exchange for a 360° macula-off RRD in his left eye. Preoperative best corrected visual acuity (VA) was hand motion. One month after surgery his VA was 0.2. At the two-month visit his VA was unchanged and cystoid macular edema (ME) was detected on optical coherence tomography (OCT) with a foveal thickness of 471 μm, which led to the diagnosis of Irvine-Gass syndrome. Two weeks later, the macular edema had increased to 634 μm. The patient was offered an intravitreal injection of triamcinolone acetonide (TA). One week after TA injection, his BCVA was 0.3 and foveal thickness had decreases to 306 μm. At the two- month visit the BCVA had increased to 0,4 and minimal intraretinal fluid was present on OCT. One month later, foveal thickness had again increased to 631 μm. At this point, the patient was offered to be treated with Ozurdex® (Allergan Inc., Irvine, CA, USA). 2 months after the injection of Ozurdex, VA was 0.4 and foveal thickness had decreased to 327 μm.

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