There is a bull’s eye pattern of depigmentation in the macula of both eyes.
Chloroquine is regularily used as an anti-malarial, and anti-inflammatory drug against rheumatoid arthritis and systemic lupus erythematosus. Prolonged use of
chloroquine may result in a degeneration of the retinal pigment epithelium
and the neurosensory retina, causing a ‘bull’s eye’ pattern of depigmentation
of the macula, and subsequent central visual loss. The cumulative dosis for a chloroquine retinopathy is about 100g.
Bellios, Nikolaus, Dr.med., Augenklinik, Friedrich-Alexander-Universität Erlangen-Nürnberg¦5, Erlangen, Deutschland
