Atlas of Ophthalmology

Radiation Retinopathy

Radiation Retinopathy
This retinopathy usually occurs 12-18 months after damage to the retina following either orbital or ocular radiotherapy. It is a microangiopathy characterized by vascular occlusion and altered vascular permeability. The fundus findings are similar to diabetic retinopathy. Cotton wool spots indicate infarction of the nerve fiber layer and there are commonly noted in the posterior pole as the nerve fiber layer is thickest there. This 37 years old gentleman had radiotherapy a year ago for nasopharyngeal carcinoma. He presented with blurring of vision of 2 weeks duration. VA of both eyes were 0.6. Right eye: multiple cotton wool spots in all 4 quadrants of the posterior pole. Dot-blot hemorrhages, flame shaped hemorrhages and sub-RPE hemorrhage. No hard exudate or neovascularization.
Tan Aik Kah, M.D., Universiti Malaysia Sarawak¦2, Kuching, Malaysia
H35.87
Retina -> Vascular Diseases (see also: Systemic Immunologic Diseases) -> Radiation Retinopathy -> Radiation Retinopathy, bilateral
7833
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