Atlas of Ophthalmology

Hypertrichosis Secondary to Long Term Latanoprost Treatment

Hypertrichosis Secondary to Long Term Latanoprost Treatment
This 70 year old gentleman has been treated for primary open-angle glaucoma for the past 3 years with latanoprost 0.05% at night. He developed bilateral hypertrichosis, poliosis and trichiasis. Latanoprost has the ability to stimulate hair follicles that are in a resting (telogen) phase into a growth (anagen) phase and induces hypertrophic changes in hair follicles. Another effect is hyperpigmentation of the iris (here not visible). The patient also has senile aponeurotic ptosis.
Tan Aik Kah, M.D., Universiti Malaysia Sarawak¦2, Kuching, Malaysia
L68.2
Glaucomas, Ocular Hypertension -> Medication-Induced Changes
7763
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