Retinal Toxicity Associated With Chloroquine (Mosaic)
Retinal Toxicity Associated With Chloroquine (Mosaic)
Adaptive Optic (Imagine Eyes, France): Image showing a significant impairment of photoreceptors compared with a control.
52 years of age, male, BCVA RA cc 0.1, LA cc 0.1.
To report the detailed clinical findings of a patient with retinal toxicity that developed secondary to the use of chloroquine over 15 years due to lupus erythematodes. The duration of hydroxychloroquine therapy was 15 years with a daily dosage of hydroxychloroquine of 250 mg per day (1993-2008). The presenting symptom was difficulty with reading.
Ophthalmologic examination, fundus photography, visual field testing, and detailed electrophysiologic assessment were undertaken and spectral domain optical coherence tomography was performed.
Ackermann, Andreas, Dr.med., Dept. Ophthalmology, Friedrich-Alexander University, Erlangen, Germany; Michelson, Georg, Prof. Dr. med., Interdisziplinäres Zentrum für augenheilkundliche Präventivmedizin, Augenklinik, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
