| Amiodarone-induced Keratopathy at OD (Colour Photography Anterior Segment) | |
| Colour Photography Anterior Segment : golden-grey deposits in a vortex fashion in corneal epithelium of both eyes, below the central cornea. Patient: 81 years of age, female, BCVA 0.5 at OD, 1/20 LT at OS. General Medical History: treatment with 200 mg amiodarone daily for 12 months for recurrent ventricular tachycardia. Ocular Medical History: AMD Purpose: to present amiodarone keratopathy Methods: Colour Photography Anterior Segment Findings: Colour Photography Anterior Segment : golden-grey deposits in a vortex fashion in corneal epithelium of both eyes, below the central cornea. Discussion: It was reported by Wasielica-Poslednik et al. (1), that amiodarone keratopathy and Fabry-induced cornea verticillata cannot be distinguished by conventional slit-lamp microscopy. They found that patients with amiodarone keratopathy showed hyper-reflective intracellular inclusions in basal epithelial cells. Amiodarone deposits were more reflective and of grossly different size. Literature: (1) Wasielica-Poslednik J, Pfeiffer N, Reinke J, Pitz S. Confocal laser-scanning microscopy allows differentiation between Fabry disease and amiodarone-induced keratopathy. Graefes Arch Clin Exp Ophthalmol. 2011 Nov;249(11):1689-96. | |
| Obermayr, Michael, Dr.med., Augenklinik, Universitätsklinikum Erlangen, Erlangen, Deutschland, Erlangen, Deutschland; Michelson, Georg, Prof. Dr. med., Interdisziplinäres Zentrum für augenheilkundliche Präventivmedizin und Imaging, Augenklinik, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Deutschland | |
| H18.5 | |
| Hornhaut / Kornea -> Medikation, Medikamente -> Amiodaron-induzierte Keratopathie (Farbphotographie Vorderabschnitt) | |
| cornea verticillata | |
| 10458 |
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